However, the absence of these players will likely impact Barcelona's performance, and the team will need to rely on other players to step up and make a difference. Frenkie de Jong, who has been ill, may be available for selection, but the team's overall performance will depend on how well they can adapt to the injuries.

Real Madrid's Kylian Mbappe has been in top form, scoring 10 goals already this season, which is at least four more than any other player in the division. The high line used by Real Madrid has been vulnerable to counterattacks, and Mbappe's pace and skill make him a significant threat to Barcelona's defense.

Goals have been a guarantee in recent El Clasico matches, with all six of the last games seeing at least four goals scored. Barcelona has scored four, five, three, and four goals against Real Madrid in their last four meetings, and the visitors will be looking to continue their winning streak.

Despite the injuries to several key players, Barcelona remains a strong contender for the win, and the team's creative midfielder, Pedri, will be crucial in determining the outcome of the match. Pedri has been instrumental in creating chances for his team, with 820 passes and 22 chances created this season.

The match is expected to be an exciting and closely contested affair, with both teams showing great resilience and determination. The outcome will depend on how well each team can adapt to the injuries and capitalize on their strengths.

Real Madrid will be missing several key defenders, including Dean Huijsen, Dani Carvajal, Antonio Rudiger, and David Alaba, and will need to rely on other players to step up and fill the gaps.

Ultimately, the El Clasico match will be a test of both teams' skills, determination, and adaptability, and it will be interesting to see how they perform under pressure.